Email Data Loss Prevention -- Proofpoint Alternatives

Best Proofpoint Alternatives for Email DLP in 2026

Email remains the most common channel for data exfiltration, both intentional and accidental. Email data loss prevention (DLP) protects against sensitive data leaving the organization through email by scanning outbound messages for confidential information, enforcing encryption policies, and preventing unauthorized data sharing. Effective email DLP goes beyond simple keyword matching to detect sensitive data patterns, apply contextual policies, and prevent accidental misdirection of sensitive emails to wrong recipients.

How It Works

1

Classify Sensitive Data Types

Identify the types of sensitive data that flow through your email system: personally identifiable information (PII), financial records, healthcare data (PHI), intellectual property, legal documents, and confidential business communications. Map each data type to its regulatory requirements (GDPR, HIPAA, PCI-DSS, SOX) and the appropriate DLP policy action (block, encrypt, warn, or audit).

2

Configure DLP Detection Policies

Create DLP policies that detect sensitive data in outbound email using content inspection, pattern matching (regex), data fingerprinting, and predefined dictionaries. Start with high-confidence policies for structured data like credit card numbers and social security numbers. Gradually expand to less structured data types using keyword proximity, document classification, and machine learning-based detection.

3

Implement Encryption and Access Controls

Configure automatic encryption for emails containing sensitive data that are sent to external recipients. Deploy email encryption that is transparent to the sender and easy for recipients to access without requiring special software. Set policies that encrypt based on content detection, recipient domain, sensitivity labels, or sender-applied classifications.

4

Deploy Misdirected Email Prevention

Implement behavioral analysis to detect when users are about to send emails to the wrong recipient — one of the most common causes of data breaches. Tessian specializes in this capability, using AI to understand each user's normal sending patterns and flagging anomalies like an unusual recipient on a sensitive thread. Configure warning prompts that give users a chance to correct mistakes before sending.

5

Monitor, Tune, and Report

Review DLP incident reports to identify patterns in policy violations: which departments trigger the most alerts, which data types are most frequently exposed, and whether violations are intentional or accidental. Tune policies to reduce false positives while maintaining coverage. Generate compliance reports demonstrating DLP effectiveness for auditors and regulators.

Top Recommendations

#1

Tessian

AI Email Security

Custom pricing / per-user licensing

Uniquely addresses accidental data loss through misdirected email prevention — detecting when users are about to send sensitive data to the wrong recipient. Behavioral AI catches both intentional exfiltration and human error, filling a gap that policy-based DLP tools miss entirely.

#2

Microsoft Defender for Office 365

Cloud Email Security

Plan 1 from $2/user/month / Plan 2 from $5/user/month / included in E5

Integrates with Microsoft Purview DLP for comprehensive data classification and email DLP policies across Microsoft 365. Native integration provides the tightest DLP coverage for M365 environments with sensitivity labels and auto-encryption.

#3

Barracuda Email Security

Enterprise Email Gateway

From $3.60/user/month / appliance pricing varies

Includes email encryption and DLP policies at a competitive price point. Provides content-based scanning with predefined DLP dictionaries for common data types like credit card numbers, social security numbers, and healthcare records.

#4

Trend Micro Email Security

Cloud Email Security

Custom pricing / per-user licensing

Email DLP with customizable policies and integration with Trend Micro's broader data protection capabilities. Offers content scanning, keyword matching, and custom regex patterns for identifying sensitive data in outbound email.

#5

Cisco Secure Email

Enterprise Email Gateway

Custom enterprise pricing / per-user licensing

Provides email DLP with content filtering, message encryption, and integration with Cisco's broader data protection policies. Best for organizations that want email DLP integrated with Cisco's network-level DLP controls.

Detailed Tool Profiles

Tessian

AI Email Security
4.1

Human layer security platform preventing inbound threats and outbound misdirected emails

Pricing

Custom pricing / per-user licensing

Best For

Organizations concerned about both inbound email threats and accidental data loss from misdirected emails and human error

Key Features
Inbound email threat detectionMisdirected email preventionAccidental data loss protectionBehavioral AI for anomaly detection+4 more
Pros
  • +Unique misdirected email prevention addresses a gap no other tool covers well
  • +Behavioral AI catches threats that gateway solutions miss
  • +Real-time coaching helps users make better security decisions
Cons
  • Now part of Proofpoint — future as standalone product uncertain
  • Not a full email gateway replacement
  • Narrower threat coverage than comprehensive email security platforms
Cloud

Microsoft Defender for Office 365

Cloud Email Security
4.4

Microsoft's native email security for Microsoft 365 with XDR integration

Pricing

Plan 1 from $2/user/month / Plan 2 from $5/user/month / included in E5

Best For

Microsoft 365-centric organizations wanting native email security with XDR integration and cost efficiency through E5 licensing

Key Features
Safe Links (URL detonation and rewriting)Safe Attachments (sandbox analysis)Anti-phishing with impersonation protectionAutomated investigation and response (AIR)+4 more
Pros
  • +Deep native integration with Microsoft 365 and Defender XDR ecosystem
  • +Included in Microsoft 365 E5 — significant cost savings for E5 customers
  • +Automated investigation and response reduces analyst workload
Cons
  • Only protects Microsoft 365 — does not support Google Workspace or other platforms
  • Detection efficacy for advanced threats historically behind Proofpoint and Mimecast
  • Configuration complexity across multiple Microsoft security portals
Cloud

Barracuda Email Security

Enterprise Email Gateway
4.1

Email threat protection platform available as gateway appliance or cloud service

Pricing

From $3.60/user/month / appliance pricing varies

Best For

Small-to-mid-market organizations wanting effective email security at a lower price point than Proofpoint or Mimecast

Key Features
Multi-layer email threat scanningLink and attachment sandboxingAnti-spam and anti-malware filteringEmail encryption and DLP+4 more
Pros
  • +Significantly lower pricing than Proofpoint and Mimecast
  • +Available as both appliance and cloud service for deployment flexibility
  • +Straightforward administration with less complexity
Cons
  • Detection efficacy below Proofpoint for advanced targeted threats
  • Cloud-native API protection less mature than gateway product
  • Reporting and analytics less sophisticated than enterprise competitors
CloudSelf-Hosted

Trend Micro Email Security

Cloud Email Security
4.1

Cloud email security gateway with AI-powered BEC detection and XDR integration

Pricing

Custom pricing / per-user licensing

Best For

Organizations wanting capable email security integrated with Trend Micro's broader Vision One XDR platform

Key Features
Writing Style DNA for BEC detectionAdvanced malware sandboxingURL time-of-click analysisCloud app protection for M365 and Google+4 more
Pros
  • +Writing Style DNA provides innovative AI-based BEC detection
  • +Strong integration with Trend Micro Vision One XDR platform
  • +Competitive pricing compared to Proofpoint and Mimecast
Cons
  • Overall detection efficacy below Proofpoint for advanced threats
  • Writing Style DNA requires training period to build executive profiles
  • Administration spread across multiple Trend Micro consoles
Cloud

Cisco Secure Email

Enterprise Email Gateway
4

Enterprise email security gateway with Cisco Talos threat intelligence integration

Pricing

Custom enterprise pricing / per-user licensing

Best For

Cisco-centric enterprises wanting email security that integrates with their existing Cisco networking and security stack

Key Features
Advanced malware protection with Talos intelligenceURL filtering and outbreak detectionForged email detection for BECData loss prevention and encryption+4 more
Pros
  • +Strong malware detection powered by Cisco Talos threat intelligence
  • +Deep integration with Cisco SecureX and broader Cisco security stack
  • +Flexible deployment options including on-premises appliance
Cons
  • BEC detection significantly behind Proofpoint and Abnormal Security
  • Administration interface feels dated and complex
  • Innovation pace slower than cloud-native email security vendors
CloudSelf-Hosted

Email Data Loss Prevention FAQ

How does Proofpoint's email DLP compare to Microsoft Purview DLP?

Proofpoint's email DLP provides content-based scanning with predefined and custom policies, integrated with its email encryption and archiving capabilities. Microsoft Purview DLP is a broader data protection platform that covers email, Teams, SharePoint, OneDrive, and endpoints with unified sensitivity labels and policies. For Microsoft 365 environments, Purview provides more comprehensive cross-platform DLP coverage. Proofpoint's advantage is deeper email-specific DLP with advanced content analysis and tighter integration with its threat protection platform.

What makes Tessian's approach to email DLP different?

Traditional DLP tools scan email content for sensitive data patterns and apply rules (block, encrypt, warn). Tessian takes a behavioral approach that understands how each user normally sends email and detects anomalies. Its misdirected email prevention catches when a user accidentally adds the wrong recipient to a sensitive thread — a data loss scenario that content-based DLP cannot detect because the content is not the problem, the recipient is. Tessian also detects intentional data exfiltration by identifying unusual email patterns like bulk forwarding to personal accounts.

Is email DLP still relevant when organizations use cloud storage?

Yes. Email remains the most common channel for sharing sensitive data externally, and outbound email DLP catches data that leaves the organization through email regardless of where it was originally stored. However, email DLP should be part of a broader data protection strategy that also covers cloud storage (OneDrive, Google Drive), messaging platforms (Teams, Slack), and endpoints. Microsoft Purview and Proofpoint both offer DLP that extends beyond email to other channels.

How do I reduce false positives in email DLP?

Start with high-confidence, low-false-positive policies targeting structured data like credit card numbers, social security numbers, and account numbers using validated regex patterns. Use proximity rules that require multiple data indicators in the same email rather than single pattern matches. Implement user-override workflows where users can justify sending detected content rather than being hard-blocked. Exclude known-safe recipients and internal domains from certain policies. Review and tune policies weekly during initial deployment, then monthly once stable.

Related Guides

Comparison

Proofpoint vs Tessian

Human layer security platform preventing inbound threats and outbound misdirected emails

Comparison

Proofpoint vs Microsoft Defender for Office 365

Microsoft's native email security for Microsoft 365 with XDR integration

Comparison

Proofpoint vs Barracuda Email Security

Email threat protection platform available as gateway appliance or cloud service

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