Enterprise Email Security Gateways -- Proofpoint Alternatives

Best Enterprise Email Gateway Alternatives to Proofpoint in 2026

Enterprise email security gateways are the traditional approach to email protection, sitting inline in the mail flow to inspect, filter, and block threats before they reach the inbox. These platforms handle the full spectrum of email threats including spam, malware, phishing, BEC, and data loss. They typically require MX record changes to route email through the gateway and offer the broadest feature sets including archiving, encryption, DLP, and compliance. These are the most direct alternatives to Proofpoint's core secure email gateway product.

Our Recommendations

1

Mimecast

Custom pricing / per-user licensing

The closest direct competitor to Proofpoint offering a similarly comprehensive platform with threat protection, archiving, awareness training, and the unique differentiator of email continuity for maintaining mail flow during outages. Best for organizations wanting a full-featured alternative with slightly easier administration.

2

Cisco Secure Email

Custom enterprise pricing / per-user licensing

Strong choice for organizations already invested in the Cisco security ecosystem, with deep SecureX integration and Talos threat intelligence. Offers both cloud and on-premises deployment options. Best for Cisco-centric enterprises wanting vendor consolidation.

3

Barracuda Email Security

From $3.60/user/month / appliance pricing varies

Provides solid email protection at a significantly lower price point than Proofpoint and Mimecast. Available as both cloud service and on-premises appliance. Best for small-to-mid-market organizations with standard email security needs and budget constraints.

Detailed Tool Profiles

Mimecast

Enterprise Email Gateway
4.3

Cloud email security platform with threat protection, archiving, and continuity

Pricing

Custom pricing / per-user licensing

Best For

Mid-to-large enterprises wanting a unified email security, archiving, and continuity platform with strong API integrations

Key Features
Targeted Threat Protection (URL, attachment, impersonation)Email continuity and failoverCloud-based email archivingSecurity awareness training+4 more
Pros
  • +Email continuity keeps mail flowing during outages — unique differentiator
  • +Strong impersonation and brand protection capabilities
  • +Unified platform covering security, archiving, and continuity
Cons
  • Detection efficacy slightly behind Proofpoint for advanced threats
  • Email archiving search performance can be slow on large datasets
  • Pricing is still premium and comparable to Proofpoint
Cloud

Cisco Secure Email

Enterprise Email Gateway
4

Enterprise email security gateway with Cisco Talos threat intelligence integration

Pricing

Custom enterprise pricing / per-user licensing

Best For

Cisco-centric enterprises wanting email security that integrates with their existing Cisco networking and security stack

Key Features
Advanced malware protection with Talos intelligenceURL filtering and outbreak detectionForged email detection for BECData loss prevention and encryption+4 more
Pros
  • +Strong malware detection powered by Cisco Talos threat intelligence
  • +Deep integration with Cisco SecureX and broader Cisco security stack
  • +Flexible deployment options including on-premises appliance
Cons
  • BEC detection significantly behind Proofpoint and Abnormal Security
  • Administration interface feels dated and complex
  • Innovation pace slower than cloud-native email security vendors
CloudSelf-Hosted

Barracuda Email Security

Enterprise Email Gateway
4.1

Email threat protection platform available as gateway appliance or cloud service

Pricing

From $3.60/user/month / appliance pricing varies

Best For

Small-to-mid-market organizations wanting effective email security at a lower price point than Proofpoint or Mimecast

Key Features
Multi-layer email threat scanningLink and attachment sandboxingAnti-spam and anti-malware filteringEmail encryption and DLP+4 more
Pros
  • +Significantly lower pricing than Proofpoint and Mimecast
  • +Available as both appliance and cloud service for deployment flexibility
  • +Straightforward administration with less complexity
Cons
  • Detection efficacy below Proofpoint for advanced targeted threats
  • Cloud-native API protection less mature than gateway product
  • Reporting and analytics less sophisticated than enterprise competitors
CloudSelf-Hosted

Proofpoint Alternatives Feature Comparison

Compare all 3 Proofpoint alternatives side-by-side across pricing, deployment, and key capabilities.

Feature
Mimecast
4.3/5
Cisco Secure Email
4/5
Barracuda Email Security
4.1/5
Pricing ModelPer-user subscriptionPer-user subscription or appliance licensePer-user subscription or appliance license
Open Source------
Cloud-Hosted+++
Self-Hosted--++
Best ForMid-to-large enterprises wanting a unified email security, archiving, and continuity platform with strong API integrationsCisco-centric enterprises wanting email security that integrates with their existing Cisco networking and security stackSmall-to-mid-market organizations wanting effective email security at a lower price point than Proofpoint or Mimecast
Key Features
  • Targeted Threat Protection (URL, attachment, impersonation)
  • Email continuity and failover
  • Cloud-based email archiving
  • Security awareness training
  • Advanced malware protection with Talos intelligence
  • URL filtering and outbreak detection
  • Forged email detection for BEC
  • Data loss prevention and encryption
  • Multi-layer email threat scanning
  • Link and attachment sandboxing
  • Anti-spam and anti-malware filtering
  • Email encryption and DLP
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Enterprise Email Security Gateways FAQ

Which enterprise email gateway has the best detection rate?

Proofpoint and Mimecast consistently rank highest in independent threat detection evaluations, with Proofpoint generally holding a slight edge for advanced targeted threats and BEC attacks. Cisco Secure Email is strong for malware detection backed by Talos intelligence. Barracuda provides solid protection for standard threats but is less effective against sophisticated, targeted attacks. For organizations facing advanced threat actors, Proofpoint and Mimecast are the top choices.

Is Mimecast a good replacement for Proofpoint?

Yes, Mimecast is the most direct replacement for Proofpoint. It offers comparable capabilities across threat protection, email archiving, and security awareness training, plus email continuity that Proofpoint does not offer. Organizations that switch from Proofpoint to Mimecast typically report similar protection with somewhat easier day-to-day administration. The main areas where Proofpoint may still lead are deep threat intelligence, BEC detection accuracy, and automated incident response workflows.

Should I choose a gateway or API-based email security?

Gateways provide the broadest protection by inspecting all email in-line before delivery, covering spam, malware, phishing, and data loss in a single platform. API-based tools deploy faster and detect social engineering attacks better, but do not provide full email security on their own. Most enterprises benefit from a gateway as the primary layer with an optional API-based tool for advanced BEC detection. If you are a smaller organization that only needs phishing protection, an API-based tool may be sufficient.

How does Barracuda compare to Proofpoint for small businesses?

Barracuda is often the better choice for small businesses due to its significantly lower pricing, simpler administration, and bundled PhishLine training at no extra cost. Proofpoint's enterprise-grade capabilities — deep threat intelligence, advanced BEC detection, and sophisticated compliance workflows — are designed for large organizations facing targeted threats. Small businesses facing standard email threats will find Barracuda provides effective protection at a fraction of the cost.

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